Chuan He Selected Research

5-hydroxymethylcytosine

11/2021	5-Hydroxymethylcytosine profiles of cfDNA are highly predictive of R-CHOP treatment response in diffuse large B cell lymphoma patients.
1/2021	5-Hydroxymethylcytosine Signatures in Circulating Cell-Free DNA as Early Warning Biomarkers for COVID-19 Progression and Myocardial Injury.
1/2020	5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic and predictive biomarkers for coronary artery disease.
1/2020	5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma.
7/2019	Author Correction: 5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers.
1/2019	5-Hydroxymethylcytosine Profiles Are Prognostic of Outcome in Neuroblastoma and Reveal Transcriptional Networks That Correlate With Tumor Phenotype.
5/2018	Circulating tumor DNA 5-hydroxymethylcytosine as a novel diagnostic biomarker for esophageal cancer.
10/2017	5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers.
1/2016	Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer.
12/2014	TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator.

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Chuan He Research Topics

Disease

53	Neoplasms (Cancer) 07/2022 - 09/2011
16	Infections 01/2022 - 11/2006
15	Carcinogenesis 01/2022 - 06/2013
12	Glioma (Gliomas) 10/2021 - 12/2014
10	Inflammation (Inflammations) 03/2022 - 01/2019
8	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2021 - 01/2009
8	Leukemia 11/2018 - 10/2012
7	Breast Neoplasms (Breast Cancer) 09/2021 - 09/2014
7	Osteoarthritis 01/2021 - 01/2013
6	Alzheimer Disease (Alzheimer's Disease) 03/2021 - 10/2020
5	Neoplasm Metastasis (Metastasis) 12/2020 - 01/2018
5	Hepatocellular Carcinoma (Hepatoma) 10/2020 - 12/2015
5	Aneurysm (Aneurysms) 10/2019 - 02/2015
4	Type 2 Diabetes Mellitus (MODY) 10/2022 - 01/2019
4	Pain (Aches) 01/2022 - 01/2014
4	Wounds and Injuries (Trauma) 12/2021 - 07/2016
4	Virus Diseases (Viral Diseases) 01/2021 - 01/2016
4	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2017
3	Stomach Neoplasms (Stomach Cancer) 01/2022 - 01/2017
3	Non-Hodgkin Lymphoma (Lymphosarcoma) 02/2021 - 06/2014
3	Brain Neoplasms (Brain Tumor) 12/2020 - 12/2014
3	Obesity 10/2011 - 10/2008
2	Hypertrophy 10/2022 - 01/2021
2	Coronary Artery Disease (Coronary Atherosclerosis) 10/2022 - 01/2020
2	Liver Diseases (Liver Disease) 01/2022 - 12/2021
2	Disease Progression 01/2022 - 04/2019
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 05/2021
2	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 11/2021 - 10/2019
2	Knee Osteoarthritis 04/2021 - 01/2019
2	Memory Disorders (Memory Loss) 03/2021 - 01/2021
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 04/2017
2	Arthritis (Polyarthritis) 10/2020 - 01/2018
2	Osteosarcoma (Osteogenic Sarcoma) 05/2020 - 03/2020
2	Fistula 01/2020 - 03/2013
2	Neuroblastoma 01/2020 - 01/2019
2	Hypoxia (Hypoxemia) 01/2020 - 12/2014
2	Liver Neoplasms (Liver Cancer) 12/2019 - 11/2019
2	Aortic Dissection 10/2019 - 06/2017
2	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2018 - 01/2009
2	Autism Spectrum Disorder 01/2018 - 10/2017
2	Brain Diseases (Brain Disorder) 11/2017 - 01/2016
2	Rett Syndrome (Rett's Disorder) 05/2017 - 10/2011

Drug/Important Bio-Agent (IBA)

37	6-methyladenineIBA 10/2022 - 11/2016
26	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2006
21	RNA (Ribonucleic Acid)IBA 01/2022 - 11/2015
17	N-methyladenosineIBA 01/2022 - 10/2011
16	Messenger RNA (mRNA)IBA 02/2022 - 01/2017
15	Cell-Free Nucleic AcidsIBA 01/2022 - 12/2015
12	Biomarkers (Surrogate Marker)IBA 01/2022 - 10/2017
12	DNA (Deoxyribonucleic Acid)IBA 08/2021 - 10/2012
11	5-hydroxymethylcytosineIBA 11/2021 - 07/2013
9	MicroRNAs (MicroRNA)IBA 02/2022 - 10/2012
9	MethyltransferasesIBA 01/2021 - 11/2016
8	Small Interfering RNA (siRNA)IBA 10/2020 - 11/2012
7	EnzymesIBA 10/2022 - 01/2009
5	CytokinesIBA 01/2021 - 12/2013
5	Biological ProductsIBA 05/2020 - 09/2011
5	Pharmaceutical PreparationsIBA 01/2017 - 01/2009
4	IronIBA 10/2021 - 01/2012
4	Long Noncoding RNAIBA 03/2021 - 01/2018
4	DioxygenasesIBA 03/2016 - 06/2013
3	PPAR gammaIBA 10/2022 - 01/2018
3	Therapeutic UsesIBA 12/2021 - 01/2018
3	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2021 - 12/2014
3	Transcription Factors (Transcription Factor)IBA 05/2021 - 12/2015
3	Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA 01/2021 - 01/2020
3	NucleotidesIBA 12/2020 - 06/2014
3	shikoninIBA 03/2020 - 01/2018
3	ChromatinIBA 01/2018 - 12/2015
3	5-Methylcytosine (5 Methylcytosine)IBA 01/2016 - 10/2012
2	5' Untranslated Regions (5' UTR)IBA 01/2022 - 12/2020
2	LigandsIBA 01/2022 - 09/2018
2	Circulating Tumor DNAIBA 01/2022 - 05/2018
2	AntioxidantsIBA 10/2021 - 02/2015
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 10/2021 - 01/2018
2	Superoxides (Superoxide)IBA 08/2021 - 01/2020
2	Adenosine (Adenocard)FDA LinkGeneric 01/2021 - 01/2020
2	Peptides (Polypeptides)IBA 12/2020 - 12/2014
2	Fetal Proteins (Fetoprotein)IBA 10/2020 - 12/2019
2	bafilomycin A1IBA 10/2020 - 01/2020
2	Chelating AgentsIBA 10/2020 - 04/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2020 - 01/2009
2	Pyruvic Acid (Pyruvate)IBA 10/2019 - 01/2018
2	Antiviral Agents (Antivirals)IBA 09/2019 - 06/2014
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2019 - 09/2018
2	CopperIBA 01/2019 - 12/2015
2	Alpha-Ketoglutarate-Dependent Dioxygenase FTOIBA 01/2019 - 11/2018
2	Capsules (Microcapsules)IBA 01/2018 - 01/2009
2	gag Gene Products (gag Protein)IBA 01/2017 - 01/2016
2	Phosphogluconate Dehydrogenase (Dehydrogenase, Phosphogluconate)IBA 11/2015 - 08/2014

Therapy/Procedure

16	Therapeutics 07/2022 - 01/2009
5	Drug Therapy (Chemotherapy) 11/2021 - 06/2014
4	Immunotherapy 01/2022 - 01/2019
3	Aftercare (After-Treatment) 01/2022 - 07/2011
3	Stents 10/2019 - 06/2017
3	Transplantation 01/2018 - 02/2013
2	Electroacupuncture 05/2021 - 03/2021
2	Hip Replacement Arthroplasty (Total Hip Replacement) 01/2021 - 01/2019
2	Osteotomy 11/2020 - 01/2018
2	Stem Cell Transplantation 10/2016 - 02/2013